Wednesday, March 27, 2013

Obama gives Secret Service its 1st female director

This undated handout photo provided by the US Secret Service shows Secret Service agent Julia Pierson. President Barack Obama will appoint the veteran Secret Service agent as the agency?s first female director, signaling his desire to change the culture at the male-dominated service, which has been marred by scandal. (AP Photo/US Secret Service)

This undated handout photo provided by the US Secret Service shows Secret Service agent Julia Pierson. President Barack Obama will appoint the veteran Secret Service agent as the agency?s first female director, signaling his desire to change the culture at the male-dominated service, which has been marred by scandal. (AP Photo/US Secret Service)

(AP) ? President Barack Obama on Tuesday named veteran Secret Service agent Julia Pierson as the agency's first female director, signaling his desire to change the culture at the male-dominated service, which has been marred by scandal.

Pierson, who most recently served as the agency's chief of staff, will take over from Mark Sullivan, who announced his retirement last month. The agency faced intense criticism during Sullivan's tenure for a prostitution scandal during preparations for Obama's trip to Cartagena, Colombia, last year.

The incident raised questions within the agency - as well as at the White House and on Capitol Hill - about the culture, particularly during foreign travel. In addition to protecting the president, the Secret Service also investigates financial crimes.

"Over her 30 years of experience with the Secret Service, Julia has consistently exemplified the spirit and dedication the men and women of the service demonstrate every day," Obama said in a statement announcing Pierson's appointment, which does not require Senate confirmation.

Homeland Security Secretary Janet Napolitano also praised Obama's "historic decision" to name Pierson as the service's first female director.

Pierson, 53, has held high-ranking posts throughout the Secret Service, including deputy assistant director of the office of protective operations and assistant director of human resources and training. She has served as chief of staff since 2008.

That same year, Pierson was awarded the Presidential Meritorious Executive Award for superior performance in management throughout her career.

She joined the Secret Service in 1983 as a special agent and previously worked as a police officer in Orlando, Fla.

"Julia is eminently qualified to lead the agency that not only safeguards Americans at major events and secures our financial system, but also protects our leaders and our first families, including my own," Obama said. "Julia has had an exemplary career, and I know these experiences will guide her as she takes on this new challenge to lead the impressive men and women of this important agency."

Thirteen Secret Service employees were caught up in last year's prostitution scandal. After a night of heavy partying in the Caribbean resort city of Cartagena, the employees brought women, including prostitutes, to the hotel where they were staying. The incident became public after one agent refused to pay a prostitute and the pair argued about payment in a hotel hallway.

Eight of the employees were forced out of the agency, three were cleared of serious misconduct and at least two have been fighting to get their jobs back.

The incident took place before Obama arrived in Colombia and the service said the president's safety was never compromised. But news of the scandal broke during his trip, overshadowing the summit and embarrassing the U.S. delegation.

Sen. Charles Grassley, R-Iowa, said the Secret Service has "lost the trust of many Americans" following the Colombia scandal. Pierson, he said Tuesday, "has a lot of work ahead of her to create a culture that respects the important job the agency is tasked with."

Sullivan issued a new code of conduct that bans employees from drinking within 10 hours of starting a shift or bringing foreign nationals back to their hotel rooms.

Sullivan apologized for the incident last year during testimony before a Senate panel.

___

Associated Press writer Alicia Caldwell contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-03-26-US-Obama-Secret-Service/id-c353cca5c72340e887d28d77e6a09a21

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Bait Car: How Hollywood Has Found A New Way To Make Money ...

Paul (not his real name) has never seen the movie The Divide. He?s a horror buff and sometimes tries to find odd and decidedly bad flicks to watch with his wife. The Divide would have fit the bill. It made $16,700 at the box office ? that amounts to about 2,100 tickets sold ? and closed with $130,839 in the bank. It cost $3 million to make.

The reviews, not surprisingly, were uniformly bad. ?Well, yes. I?m another person who got suckered into watching this piece of garbage. The most important thing you need to know about this movie is that it?s just not worth spending two hours of your life to watch it. It?s just bad,? wrote one IMDb user.

?The characters are so clich? and the dialogue is so poorly written that any self-respecting horror lover would quickly roll their eyes, eject the DVD and watch The Mist on cable before falling asleep in his or her clothes,? wrote another. It?s one of those movies for a very specific audience. For guys like Paul.

Paul also admits to occasionally torrenting hard-to-find films. But he?s never seen The Divide. He never downloaded it. I believe him.

However, a month ago, Paul got a letter from his ISP accusing him of torrenting a copy of the file at midnight one lazy evening. His ISP informed him that his IP address, an identifier that, in truth, constantly changes for most Internet users, was identified as being part of the download. Because of this, he?s being sued.

Paul is now in the strange world of copyright trolls, companies that produce or license content for the sole purpose of suing users who pirate it ? even inadvertently.

How did Paul get caught? And what is his recourse now that he?s been fingered as a pirate? The answers to those questions are mired in some of the most contentious legal wrangling ever and is the basis of an entire industry, one dedicated to producing Internet-based ?bait cars? that allow copyright holders to see a trickle of money for even the arguably worst content imaginable.
what happened?First, a brief primer on BitTorrent. When a file, a document, say, is put on BitTorrent, a user makes it available as a seed. This seed is downloaded a few times by other users ? peers ? and then, once enough copies are available, the peers begin serving up parts of that file. Think of it as a group of people sharing a candle. The first person lights another person?s candle and so on. Eventually, the holder of the original flame is forgotten and the flame is self-perpetuating. While this metaphor isn?t completely accurate, it works well enough.

According to Paul?s ISP, then, Paul?s computer held the flame for a brief period, serving up all or some of The Divide to other users. Whether this is true or not is the biggest problem in this sort of copyright law. If Paul served up a packet inadvertently, is it his fault? If he only served up one packet versus the entire file, is he at fault? And how can ISPs prove beyond a doubt that Paul is the culprit here? They can?t.

The DMCA complaint Paul received came from R&D Film 1, LCC, represented by attorneys Michael Heirl and?Todd Pankhurst of Hughes Socol Piers Resnick & Dym, Ltd. in Chicago. The complaint cited him by IP address and cited this file, a 720p Blu-Ray rip release by BHRG. In the case of The Pirate Bay, the file was seeded by a user called maximersk, who has seeded a number of videos and television programs from various ?groups.?

It is important to note that The Divide is still available for download.
Screen Shot 2013-03-23 at 11.03.29 AM
Files produced by various groups ? in this case BHRG ? differ in quality and availability. There are many versions of The Divide, including higher- and lower-resolution copies.

But only this copy is seeing lawsuits thrown at it. If the lawsuit defendants had picked another copy, any other copy, they would have been in the clear. Clearly this particular 720p, high-resolution copy of The Divide is being watched. Every time someone shared a little bit of it, chances are one of the seeders ?caught? the IP address of the requester. The seeder made a list, forwarded that list to the appropriate ISPs, and then prepared their case. The IP addresses are sent with a timestamp (which could be wrong) and, as we all know, IP addresses are ephemeral things. Again, Paul was no angel, but he got caught in a dragnet that had little to do with him.

?If entrapment wasn?t done by government entities this would be entrapment,? said Robert Z. Cashman, a patent attorney who runs a website dedicated to researching copyright trolls.
who did it?Ross Dinerstein, the R and the D in R&D, is an indie film producer and a nice guy. You can see him chatting about a movie called The Pact here. He lives in Los Angeles and has the round, boyish face of a Hollywood business man focused more on doing deals than going gluten-free. He was executive producer for Jiro Dreams of Sushi, a beautiful piece of indie documentary filmmaking that could be considered a masterpiece. I spoke to him and he laid out his case.

?I?m a producer. I don?t have the bandwidth to chase pirates, so I hired a specialist to handle it,? he said. ?As far as I know, [the people being sued] get trapped by stealing copyrighted material which is not a good idea.?

It?s hard to dump the blame on Dinerstein or anyone like him. While he does see a small amount of money from these lawsuits, he has essentially outsourced their enforcement to a company called GuardaLey, a firm that rose to infamy for offering software products and anti-piracy services whose ?evidence gathering techniques are far from optimal.? Attorney Jason Sweet told TorrentFreak:

?GuardaLey knew of the flaw, but continued using it to identify infringers. We haven?t seen anything that would indicate they?ve corrected the problem or are using different methods. I believe they?ve even made statements to the contrary ? that they use the same tech for all of their cases.?

GuardaLey did not respond to requests for an interview, and R&D Film 1 LLC?s counsel at Hughes Socol Piers Resnick & Dym, Ltd. said ?No comment.?

Disconnecting Dinerstein from GuardaLey is obviously problematic, but let?s assume, for the sake of sanity, that the movie was made in good faith and that his goal was to show people a good time. Who, then, is at fault? Dinerstein for wanting what is, by all rights, his? Or GuardaLay for essentially expressing a level of incompetence that would get most software services houses fired?

Lawsuits like this one started cropping up in 2010 and have risen in intensity since. Pop over here and search for copyright cases with the party name ?Doe 1-? in any court. You?ll see quite a few cases, many of them dealing with exactly this type of situation.
Screen Shot 2013-03-23 at 10.43.58 AM

Remember that it doesn?t have to be this way. The easiest way to have something removed from the Internet is through a simple DMCA filing. Takedown notices like this one to Google are addressed almost immediately, which is often a boon for copyright holders, but is also a club for those wishing to hide information, as was evidenced in a case against a WordPress user whose plagiarist requested a takedown notice for blog posts they had copied.

There is obviously little monetary value in these notices, but they do remove offending content, for the most part, in a few keystrokes. It?s a method of first resort and makes the most sense for copyright holders.

GuardaLey has a stable of law firms that send out these letters in hopes that customers will settle. If they don?t ? if the cases go to court or they are ignored ? they stand to lose money. The sweet spot, then, is in those too cowed not to react and too confused to find legal representation.

?My folks just got served a subpoena,? wrote the relative of one of the victims. ?They are elderly and I know did nothing wrong; possibly someone else using their IP address. I?m thinking either hiring an attorney as a shield, or doing nothing and praying it goes away. I will not have them appear in court or settle. What do you suggest??

Others, like a 16-year-old defendant, are worried the lawsuit will ruin their family. Still others see it as a scam.

One user received a subpoena after watching a Mr. Rogers episode online. ?There is no reason for them to come after me, my kids, or any of the other thousand viewers, unless stopping ?piracy? for copyright trolls is not their real intent.?

Copyright trolling efforts like these are not new. Cashman has been following them for years.

?Copyright trolls are generally production studios and/or they?re enterprising attorneys who have decided that it is more profitable for them to sue defendants and elicit multi-thousand-dollar settlements from accused defendants rather than sell tickets or copies of their copyrighted films at retail or discount prices,? he said. ?A porn production company could make millions suing defendants rather than promoting $20 per-month memberships at their websites. For these reasons, these lawsuits in their post-Napster, post-Grokster form took shape.?

But what right do these trolls have to ask for outrageous sums? In copyright law there is a duality. On one hand, you can say that the studio is out one paying customer ? $20 at most for the ticket and a few bucks more for popcorn. On the other, you can say that the downloader has, inadvertently, become a pirate distributor. That?s partially why it?s easy for these guys to go after BitTorrent users (that and the ubiquity of the service.)

?Their filings for copyright infringement are probably correct ? if a downloader made an unauthorized copy of a copyrighted file, they could probably be held liable for copyright infringement. I am hedging on this statement because I would like to see the laws limited to those who enjoy a financial gain from this infringement, and I do not consider the ?loss of a movie ticket or sale? to be substantial enough to sue a defendant for $150,000,? said Cashman.

So somehow Paul?s IP address got on R&D/GuardaLey?s list. They sent a letter to the ISP asking for the specific data pertaining to the accused user, and the ISP, thanks to the DMCA, is forced to comply. In fact, companies will cry ?The DMCA made me do it? at the drop of a hat these days, another issue that frustrates content producers to no end.

So what now?
fighting back?Don?t be fooled ? these trolls can be fought using the same arguments as any of the others. An IP address still does not conclusively link to the subscriber as the downloader,? said Cashman.

?Each of these cases suffered from the same issues which would prevent them from going to trial ? lack of personal jurisdiction, improper joinder of accused defendants, and that there were clear patterns in the rulings of the judges across the U.S. where they were clearly misunderstanding what was the real intention of these copyright trolls, and they were denying motions to quash and attempts of the internet users to prevent the copyright trolls from obtaining their contact information,? he said.

Jeffrey Antonelli, an anti-troll lawyer, told us that before those attacked do anything they should confirm that their computers are compromised or that a relative hasn?t been visiting The Pirate Bay without their knowledge.

Then you have to gamble. Do you hire a lawyer and forge ahead or ignore the notice?

?I have represented a number of people who were sued because they ignored the letters. It?s about trying to determine that chance, it?s difficult, and it would be helpful to have legal advice. You can be well-informed by reading the relevant sources. Copyright Trolls and Die, Troll, Die are both good sources and both are being sued by some copyright trolls,? he said.

Again, is this Dinerstein?s fault? No, said Antonelli. ?Starting from the presumption that copyright owners ? bona fide business owners that are providing content. With those assumptions, I don?t think it?s necessarily bad.?I do have issues with the manner in which those people are doing their investigations/litigation and with the selection of people they actually decide to sue.?

Antonelli said Paul is looking at a claim of about $500-$750.

?Other law firms charge more, my firm is able to charge less. Litigation is quite a bit more expensive. Litigation can easily be up to $5,000-$6,000 and can quickly escalate to $50,000 if you?re the main defendant. It?s very burdensome. There should be strict rules on the ability to enforce copyrights through ISP subpoenas.?

In the end, copyright trolling is a sneak attack on folks who may or may not be doing anything wrong. While certainly The Divide is a piece of intellectual property that deserves protection, things break down when it is used as bait to gather lucrative lawsuits. Entire film studios produce second-rate movies to, presumably, show on Netflix and other services and, sadly, use to power these lawsuits. While perhaps the The Divide isn?t such a movie, the chances look good.

screamIt appears to me as if these movie studios have been making second-rate movies for some time, more as a hobby as far as I?m concerned. Setting up a holding company and transferring the copyright to the holding company so that they could sue for copyright infringement appears to be a ?business model? of what is known as ?IP monetization? that lawyers are so excited about.

?In other words, they say: ?It?s a bad economy, so let?s threaten to, but not sue the pants off of anyone who downloads our content,?? he said.

Sadly, for folks like Paul, sometimes that strategy works.

With reporting by Michael Seo

[Illustration: Bryce Durbin]

Source: http://techcrunch.com/2013/03/25/how-copyright-trolls-run-bait-car-operations-to-grab-pirates/

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Tuesday, March 26, 2013

North Dakota governor signs 'heartbeat' abortion ban

By Dave Thompson

BISMARCK, North Dakota (Reuters) - North Dakota on Tuesday adopted the most restrictive abortion law in the United States, as the governor signed a bill that bans the procedure in most cases once a fetal heartbeat can be detected, as early as six weeks.

Supporters of abortion rights said they would challenge the measure in court.

Governor Jack Dalrymple on Tuesday also signed a bill that bans abortions based solely on genetic abnormalities, the first state ban of its kind, or based on the gender of the fetus.

North Dakota is the latest state to pass measures to restrict abortions. Arkansas lawmakers earlier in March approved a ban on most abortions after 12 weeks of pregnancy that could take effect in August if it survives expected legal challenges.

Several states ban most abortions after 20 weeks of pregnancy.

Dalrymple, a Republican in a state with a Republican-controlled legislature, said the constitutionality of North Dakota's effective ban at six weeks into pregnancy was an open question. He said lawmakers should appropriate money to a litigation fund for the state attorney general to defend against any possible challenges to the law.

The "heartbeat" bill provides exceptions if an abortion would prevent the death or irreversible impairment of a pregnant woman, but provides no exception for rape. It sets up a direct challenge to the Supreme Court's decision in Roe v. Wade that legalized abortion in 1973.

"These are bills that have passed the legislature. This is what they want to do," Dalrymple told reporters in Dickinson, North Dakota. "They have a legislative right to find out if these laws can stand."

CHALLENGE PLANNED

The Center for Reproductive Rights said it plans to file a legal challenge to the six-week ban before it takes effect on August 1 on behalf of North Dakota's only clinic that provides abortions, the Red River Women's Clinic in Fargo.

"North Dakota has set a new standard for extreme hostility toward the rights and health of women, the U.S. Constitution, and 40 years of Supreme Court precedent," Nancy Northup, the center's president and chief executive, said in a statement.

"We will not allow this frontal assault on fundamental reproductive rights to go unchallenged," Northup said.

Roe v. Wade and later Supreme Court decisions have found that states cannot ban abortions before the fetus is viable.

Dalrymple on Tuesday also signed a third bill on abortions, requiring physicians who perform abortions in the state to have privileges at a nearby hospital that also permits abortions in its facility.

(Additional reporting by David Bailey in Minneapolis and Ernest Scheyder in Dickinson, North Dakota; editing by Scott Malone and Leslie Adler)

Source: http://news.yahoo.com/north-dakota-governor-signs-heartbeat-abortion-ban-165447884.html

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Laser empties atoms from the inside out

Mar. 25, 2013 ? An international team of plasma physicists has used one of the world's most powerful lasers to create highly unusual plasma composed of hollow atoms.

The experimental work led by scientists from the University of York, UK and the Joint Institute for High Temperatures of Russian Academy of Sciences demonstrated that it is possible to remove the two most deeply bound electrons from atoms, emptying the inner most quantum shell and leading to a distinctive plasma state.

The experiment was carried out using the petawatt laser at the Central Laser Facility at the Science and Technology Facilities Council (STFC) Rutherford Appleton Laboratory to further understanding of fusion energy generation, which employs plasmas that are hotter than the core of the Sun.

The results are reported in the journal Physical Review Letters.

A hollow atom occurs when an electron buried in an atom is removed, usually by being hit by another electron, creating a hole while leaving all the other electrons attached. This process creates plasma, a form of ionised gas. An X-ray is released when the hole is filled.

Normally the process involves removing electrons from the outer shells of atoms first and working inwards. The team of scientists demonstrated a new mechanism for creating hollow atoms that involved emptying atoms from the inside out.

The experimental work used an intense laser, which at one petawatt delivers approximately 10,000 times the entire UK national grid, delivered in a thousand-billionth of a second, onto an area smaller than the end of a human hair.

Dr Nigel Woolsey, from the York Plasma Institute, Department of Physics, at the University of York was the Principal Investigator for the experimental work.

Dr Woolsey said: "At such extraordinary intensities electrons move at close to the speed of light and as they move they create perhaps the most intense X-rays ever observed on Earth. These X-rays empty the atoms from the inside out; a most extraordinary observation and one that suggests the physics of these interactions is likely to change, as lasers become more powerful."

Analysis and theoretical work was led by the Los Alamos National Laboratory, USA and Osaka University, Japan.

The analysis showed the mechanism for hollow atom generation was not due to the collision of electrons or driven by the laser photons, but was driven by the resulting radiation field from the interaction.

Lead author Dr James Colgan, from the Los Alamos National Laboratory, said: "The conditions under which the hollow atoms were produced were highly non-equilibrium and the production mechanism was quite surprising. These results indicate that a little-explored region of physics is now starting to become accessible with the unprecedented intensities reached by the world's leading laser facilities."

Co-author Dr Alexei Zhidkov, from Osaka University, said: "This experiment has demonstrated a situation where X-ray radiation dominates the atomic physics in a laser-plasma interaction; this indicates the importance of X-ray radiation generation in our physics description. Future experiments are likely to show yet more dramatic effects which will have substantial implications for diverse fields such as laboratory-based astrophysics."

If the scientific and technological challenges can be overcome, fusion offers the potential for an effectively limitless supply of safe, environmentally friendly energy. The experimental work was designed to further scientists understanding of how intense lasers can create electron beams with speeds close to the speed of light, then use these beams to heat fusion fuel to thermonuclear temperatures.

Co-author Dr Sergey Pikuz, from the Joint Institute for High Temperatures RAS, said: "The measurements, simulations, and developing physics picture are consistent with a scenario in which high-intensity laser technology can be used to generate extremely intense X-ray fields. This demonstrates the potential to study properties of matter under the impact of intense X-ray radiation."

Co-author Rachel Dance, a University of York PhD physics student, said: "This was a very dynamic experiment which led to an unexpected outcome and new physics. The hollow atom diagnostic was set to measure the hot electron beam current generated by the laser, and the results that came out of this in the end, showed us that the mechanism for hollow atom generation, was not collisional or driven by the laser photons, but by the resulting radiation field from the interaction."

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Story Source:

The above story is reprinted from materials provided by University of York.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. J. Colgan, J. Abdallah, A. Ya. Faenov, S. A. Pikuz, E. Wagenaars, N. Booth, O. Culfa, R. J. Dance, R. G. Evans, R. J. Gray, T. Kaempfer, K. L. Lancaster, P. McKenna, A. L. Rossall, I. Yu. Skobelev, K. S. Schulze, I. Uschmann, A. G. Zhidkov, N. C. Woolsey. Exotic Dense-Matter States Pumped by a Relativistic Laser Plasma in the Radiation-Dominated Regime. Physical Review Letters, 2013; 110 (12) DOI: 10.1103/PhysRevLett.110.125001

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/aIbLFRa7YGQ/130325093528.htm

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SEC approves Nasdaq's Facebook IPO payment plan

NEW YORK?The Securities and Exchange Commission said Monday that it has approved a plan by the Nasdaq stock exchange to pay $62 million in reimbursements to investment firms that lost money because of technical problems during Facebook's initial public offering last year.

The Nasdaq had said in June that it would pay $40 million but later increased the amount to $62 million.

Facebook went public May 18 amid great fanfare, but computer glitches at the Nasdaq delayed the start of trading and threw the debut into chaos. Technical problems kept many investors from buying shares that morning, selling them later in the day or even from knowing whether their orders went through. Some said they were left holding shares they didn't want.

Facebook's stock originally priced at $38 and closed that first day at $38.23 after going as high as $45. The lackluster close disappointed investors who had hoped for a first-day pop. Nasdaq has said that it was embarrassed by the glitches, but that they didn't contribute to the underwhelming returns.

Shares of Menlo Park, Calif.-based Facebook Inc. fell 39 cents to $25.34 in Monday morning trading. The stock has not hit its IPO price since the first day of trading.

Source: http://feeds.denverpost.com/~r/dp-business/~3/CGQgqH5GGvM/sec-approves-nasdaqs-facebook-ipo-payment-plan

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NCAA Tournament Capsules

Capsules from the NCAA tournament Saturday.

---

BRIDGEPORT REGIONAL

No. 2 KENTUCKY 61, No. 15 NAVY 41

DeNesha Stallworth scored 18 points and Jennifer O'Neill added nine of her 12 points in the second half to lead Kentucky over Navy.

The Wildcats (28-5) trailed by one at the half before O'Neill, who grew up in New York, took over. She hit a quick 3-pointer to start a 12-2 run. The sophomore guard had seven points, a steal and an assist during the burst.

Kentucky had been off for 14 days since losing in the SEC tournament title game and looked rusty early on. Two-time SEC player of the year A'dia Mathies didn't have a field goal for the first time in her career.

Alix Membreno and Jade Geif scored nine each to lead Navy (21-12), which was trying to become the first 15 seed to win a game in NCAA tournament history.

No. 3 NORTH CAROLINA 59, No. 14 ALBANY 54

NEWARK, Del. (AP) - Tierra Ruffin-Pratt scored a career-high 30 points, and North Carolina squeezed past Albany to stagger into the second round of the NCAA tournament.

North Carolina trailed 28-23 at halftime and 48-44 with just under 10 minutes left before rallying behind Ruffin-Pratt, who scored 17 of the Tar Heels' final 21 points - including two clinching free throws with 10.8 seconds left.

Waltiea Rolle had 14 points and 14 rebounds for North Carolina (29-6), which will next face sixth-seeded Delaware (31-3) on Tuesday night. Delaware advanced with a 66-53 win over West Virginia.

No. 6 DELAWARE 66, No. 11 WEST VIRGINIA 53

NEWARK, Del. (AP) - Elena Delle Donne scored 33 points and led a second-half surge that carried Delaware past West Virginia.

Playing on their home floor before a sellout crowd, the Blue Hens trailed 33-26 at halftime before bouncing back to extend their school-record winning streak to 26 games.

Delaware (31-3) had never won an NCAA tournament game before last year. The Blue Hens have yet to reach the round of 16, a milestone they will seek to accomplish Tuesday night against either North Carolina or Albany.

Delle Donne, a 6-foot-5 senior, scored 17 points after halftime. She finished 10 for 24 from the floor, went 12 for 13 at the foul line and had seven rebounds.

Ayana Dunning had 15 points and 10 rebounds for 11th-seeded West Virginia (17-14), which closed the season with a four-game losing streak.

No. 7 DAYTON 96, No. 10 ST. JOHN'S 90, 2 OT

Andrea Hoover scored a career-high 24 points and Dayton outlasted St. John's.

It was the first double overtime game in the tournament since 2000 when Vanderbilt beat Kansas.

Brittany Wilson hit a 3-pointer and Kelley Austria had a three-point play to make it 90-86 with 2:11 left in the second extra period. After St. John's failed to score, Olivia Applewhite added a basket with 47 seconds left to seal the win.

The Red Storm (18-13) trailed by 13 with 5:30 left in regulation before rallying. Nadirah McKenith hit a layup with one-tenth of a second left in regulation to force OT. Dayton's Amber Deane tied it with 15 seconds left in OT to force a second one

McKenith led her team with 22 points, 10 assists and nine rebounds before fouling out.

---

NORFOLK REGIONAL

No. 2 DUKE 67, No. 15 HAMPTON 51

DURHAM, N.C. (AP) - Tricia Liston scored 13 of her 20 points in the second half and Duke pulled away to beat Hampton.

Elizabeth Williams added 18 points and Haley Peters finished with 12 points and 10 rebounds for the Blue Devils (31-2).

Source: http://www.miamiherald.com/2013/03/24/3304491/ncaa-tournament-capsules.html

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Monday, March 25, 2013

UW researchers discover the brain origins of variation in pathological anxiety

UW researchers discover the brain origins of variation in pathological anxiety [ Back to EurekAlert! ] Public release date: 25-Mar-2013
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Contact: Susan Lampert Smith
ssmith5@uwhealth.org
608-890-5643
University of Wisconsin-Madison

Madison, Wis. New findings from nonhuman primates suggest that an overactive core circuit in the brain, and its interaction with other specialized circuits, accounts for the variability in symptoms shown by patients with severe anxiety. In a brain-imaging study to be published online today in the Proceedings of the National Academy of Sciences (PNAS), researchers from the University of Wisconsin School of Medicine and Public Health describe work that for the first time provides an understanding of the root causes of clinical variability in anxiety disorders.

Using a well-established nonhuman primate model of childhood anxiety, the scientists identified a core circuit that is chronically over-active in all anxious individuals, regardless of their particular pattern of symptoms. They also identified a set of more specialized circuits that are over- or under-active in individuals prone to particular symptoms, such as chronically high levels of the stress-hormone cortisol.

"These findings provide important new insights into altered brain functioning that explain why people with anxiety have such different symptoms and clinical presentations, and it also gives us new ideas, based on an understanding of altered brain function, for helping people with different types of anxiety,'' says Dr. Ned Kalin, senior author, chair of Psychiatry and director of the HealthEmotions Research Institute.

"There is a large need for new treatment strategies, because our current treatments don't work well for many anxious adults and children who come to us for help."

In the study, key anxiety-related symptoms were measured in 238 young rhesus monkeys using behavioral and hormonal measurement procedures similar to those routinely used to assess extreme shyness in children. Young monkeys are ideally suited for these studies because of their similarities in brain development and social behavior, Kalin noted. Variation in brain activity was quantified in the monkeys using positron emission tomography (PET) imaging, a method that is also used in humans.

Combining behavioral measures of shyness, physiological measures of the stress-hormone cortisol, and brain metabolic imaging, co-lead authors Dr. Alexander Shackman, Andrew Fox, and their collaborators showed that a core neural system marked by elevated activity in the central nucleus of the amygdala was a consistent brain signature shared by young monkeys with chronically high levels of anxiety. This was true despite striking differences across monkeys in the predominance of particular anxiety-related symptoms.

The Wisconsin researchers also showed that young monkeys with particular anxiety profiles, such as high levels of shyness, showed changes in symptom-specific brain circuits. Finally, Shackman, Fox, and colleagues uncovered evidence that the two kinds of brain circuits, one shared by all anxious individuals, the other specific to those with particular symptoms, work together to produce different presentations of pathological anxiety.

The new study builds upon earlier work by the Kalin laboratory demonstrating that activity in the amygdala is strongly shaped by early-life experiences, such as parenting and social interactions. They hypothesize that extreme anxiety stems from problems with the normal maturation of brain systems involved in emotional learning, which suggests that anxious children have difficulty learning to effectively regulate brain anxiety circuits. Taken together, this line of research sets the stage for improved strategies for preventing extreme childhood anxiety from blossoming into full-blown anxiety disorders.

"This means the amygdala is an extremely attractive target for new, broad-spectrum anxiety treatments,'' says Shackman. "The central nucleus of the amygdala is a uniquely malleable substrate for anxiety, one that can help to trigger a wide range of symptoms."

The work also suggests more specific brain targets for different symptom profiles. Such therapies could range from new, more selectively targeted medications to intensive therapies that seek to re-train the amygdala, ranging from conventional cognitive-behavioral therapies to training in mindfulness and other techniques, Shackman noted. To further understand the clinical significance of these observations, the laboratory is conducting a parallel study in young children suffering from anxiety disorders.

###

Other members of the research team include Dr. Jonathan Oler, Steven Shelton and Dr. Richard Davidson, all of the University of Wisconsin-Madison. Dr. Shackman is in the process of moving to the University of Maryland as an assistant professor. An abstract is available here: http://www.pnas.org/


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UW researchers discover the brain origins of variation in pathological anxiety [ Back to EurekAlert! ] Public release date: 25-Mar-2013
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Contact: Susan Lampert Smith
ssmith5@uwhealth.org
608-890-5643
University of Wisconsin-Madison

Madison, Wis. New findings from nonhuman primates suggest that an overactive core circuit in the brain, and its interaction with other specialized circuits, accounts for the variability in symptoms shown by patients with severe anxiety. In a brain-imaging study to be published online today in the Proceedings of the National Academy of Sciences (PNAS), researchers from the University of Wisconsin School of Medicine and Public Health describe work that for the first time provides an understanding of the root causes of clinical variability in anxiety disorders.

Using a well-established nonhuman primate model of childhood anxiety, the scientists identified a core circuit that is chronically over-active in all anxious individuals, regardless of their particular pattern of symptoms. They also identified a set of more specialized circuits that are over- or under-active in individuals prone to particular symptoms, such as chronically high levels of the stress-hormone cortisol.

"These findings provide important new insights into altered brain functioning that explain why people with anxiety have such different symptoms and clinical presentations, and it also gives us new ideas, based on an understanding of altered brain function, for helping people with different types of anxiety,'' says Dr. Ned Kalin, senior author, chair of Psychiatry and director of the HealthEmotions Research Institute.

"There is a large need for new treatment strategies, because our current treatments don't work well for many anxious adults and children who come to us for help."

In the study, key anxiety-related symptoms were measured in 238 young rhesus monkeys using behavioral and hormonal measurement procedures similar to those routinely used to assess extreme shyness in children. Young monkeys are ideally suited for these studies because of their similarities in brain development and social behavior, Kalin noted. Variation in brain activity was quantified in the monkeys using positron emission tomography (PET) imaging, a method that is also used in humans.

Combining behavioral measures of shyness, physiological measures of the stress-hormone cortisol, and brain metabolic imaging, co-lead authors Dr. Alexander Shackman, Andrew Fox, and their collaborators showed that a core neural system marked by elevated activity in the central nucleus of the amygdala was a consistent brain signature shared by young monkeys with chronically high levels of anxiety. This was true despite striking differences across monkeys in the predominance of particular anxiety-related symptoms.

The Wisconsin researchers also showed that young monkeys with particular anxiety profiles, such as high levels of shyness, showed changes in symptom-specific brain circuits. Finally, Shackman, Fox, and colleagues uncovered evidence that the two kinds of brain circuits, one shared by all anxious individuals, the other specific to those with particular symptoms, work together to produce different presentations of pathological anxiety.

The new study builds upon earlier work by the Kalin laboratory demonstrating that activity in the amygdala is strongly shaped by early-life experiences, such as parenting and social interactions. They hypothesize that extreme anxiety stems from problems with the normal maturation of brain systems involved in emotional learning, which suggests that anxious children have difficulty learning to effectively regulate brain anxiety circuits. Taken together, this line of research sets the stage for improved strategies for preventing extreme childhood anxiety from blossoming into full-blown anxiety disorders.

"This means the amygdala is an extremely attractive target for new, broad-spectrum anxiety treatments,'' says Shackman. "The central nucleus of the amygdala is a uniquely malleable substrate for anxiety, one that can help to trigger a wide range of symptoms."

The work also suggests more specific brain targets for different symptom profiles. Such therapies could range from new, more selectively targeted medications to intensive therapies that seek to re-train the amygdala, ranging from conventional cognitive-behavioral therapies to training in mindfulness and other techniques, Shackman noted. To further understand the clinical significance of these observations, the laboratory is conducting a parallel study in young children suffering from anxiety disorders.

###

Other members of the research team include Dr. Jonathan Oler, Steven Shelton and Dr. Richard Davidson, all of the University of Wisconsin-Madison. Dr. Shackman is in the process of moving to the University of Maryland as an assistant professor. An abstract is available here: http://www.pnas.org/


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-03/uow-urd032513.php

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